Eur J Pediatr. Aug;(8) Epub Jun 4. Periventricular leucomalacia: a review. Blumenthal I(1). Author information: (1)The Royal Oldham. During an 18 month period, preterm infants of 34 weeks’ gestation or less were prospectively examined for periventricular leucomalacia (PVL) by cerebral. Periventricular leucomalacia is the term used to describe cerebral infarctions occurring near the lateral ventricles in neonates. The lesion was first described by.
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Periventricular leucomalacia: a review.
Because white matter injury in the periventricular region can result in a variety of deficits, neurologists must closely monitor infants diagnosed with PVL in order to determine the severity and extent of their conditions. Periventricular leukomalacia in children. Effect of neonatal periventricular haemorrhage on neurodevelopmental outcome. As previously noted, there are often few signs of white matter injury in newborns.
Thank you for updating your details. Only recently have newer imaging techniques identified both a diffuse and focal component of white matter damage. A form of neonatal anoxic encephalopathy. Periventricular leucomalacia is a condition that causes lifelong disability and considerable economic burden. A method for neurologic evaluation within the first year of life. Robbin’s Review of Pathology. Case 2 Case 2.
Periventricular leucomalacia and neurodevelopmental outcome in preterm infants.
Retrieved from ” https: Periventricular leukomalacia PVL is a form of white-matter brain injury, characterized by the necrosis more often coagulation of white matter near the lateral ventricles. An emphasis on prenatal health perivehtricular regular medical examinations of the mother can also notably decrease the risk of PVL.
Children and adults may be quadriplegicexhibiting a loss of function or paralysis of all four limbs.
Immediately after an injury, the nervous system generates “pro-inflammatory” cytokineswhich are molecules used to coordinate a response to the insult. Progressive necrosis of the periventricular tissue with resulting enlargement of the ventricles is called end-stage PVL. You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Premature infants often exhibit visual impairment and motor deficits in eye control immediately after birth.
Edit article Share article View revision history. The most immature infants with diffuse injury develop white matter atrophy and ventriculomegaly; others with focal injury have cyst formation, resorption and gliosis.
Articles Cases Courses Quiz. Risk factors in the development of intraventricular haemorrhage in the preterm neonate.
Periventricular leukomalacia – Wikipedia
These hypoxic-ischemic incidents can cause damage to the blood brain barrier BBBa system of endothelial cells and glial cells that regulates the flow of nutrients to the brain. Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome pleural disease Pneumothorax Pneumomediastinum Wilson—Mikity syndrome Bronchopulmonary dysplasia.
Gray baby syndrome muscle tone Congenital hypertonia Congenital hypotonia. Respiratory Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome pleural disease Pneumothorax Pneumomediastinum Wilson—Mikity syndrome Bronchopulmonary dysplasia.